Research Support
Ongoing Research Support
R01-HL123762, NIH/NHLBI, Lindner (PI), Co-Investigator
Augmentation of Tissue Perfusion in PAD with Ultrasound-mediated Cavitation
The major goal of this project is to explore how ultrasound-mediated cavitation of microbubble contrast agents can produce augmentation in tissue perfusion, and to assess the mechanism by which flow increases.
R01 HL136373-01A1, NIH/NHLBI, Pamir (PI), Co-Investigator
Identification of the role of HDL function in human cardiovascular disease and stroke through proteomics and genetics
This project aims to study the cardiovascular risk prediction ability of HDL’s cholesterol efflux function compared to HDL cholesterol levels in stroke patients from a bi-racial cohort, REGARDS.
—-, Department of Veterans Affairs MVP, Luoh (PI), Co-Investigator
Predicting the Breast Cancer Risk for Women Veterans
The goal of this proposal is to extract SNP information from the Million Veteran Program data and together with demographic, life style, family history, and other information obtained from the MVP and clinical data, to build a breast cancer risk prediction model that can be applied to women veterans enrolled in the MVP.
17GRNT33670428, AHA, Tereshchenko (PI), Co-Investigator
Global electrical heterogeneity and clinical outcomes
The goal of this proposal is to validate global electrical heterogeneity sudden cardiac death risk score in OHSU health care population.
17GRNT33670334, AHA, Broberg (PI), Co-Investigator
The Systemic Right Ventricle: Risks and Outcomes of Congestive Heart Failure
The goal of this project is see the risks and Outcomes of Congestive Heart Failure in patients with a Systemic Right Ventricle.
R21-NS094833-01, DHHS/NIH/IGNITE, Stenzel-Poore (PI), Biostatistician
Development of Poly ICLC for neuroprotection against ischemic brain injury
This proposal seeks to advance PolyICLC, a compound that has shown efficacy as a prophylactic treatment in mice, through our novel nonhuman primate stroke model, allowing for eventual translation into patients at risk of brain ischemic injury.
P30 CA69533-19, NIH/NCI, Druker (PI), Faculty
OHSU Knight Cancer Institute
To support the Cancer Institute at Oregon Health & Science University, its programs, shared resources, and administration. Shared resources include; cancer pathology, flow cytometry, molecular biology, transgenic/gene knockout, gene array, clinical research management, biostatistics and informatics. The instruments of the Institute foster interdisciplinary coordination and collaboration of cancer research faculty at OHSU in basic, clinical, and population research.
Completed Research Support
14NSBRI1-0025, NSBRI, Lindner (PI), Co-Investigator
Biomarker assessment for identifying heightened risk for cardiovascular complications during long-duration space missions
With the proposed work we will explore new paradigms for: (a) predicting risk for developing atherosclerotic complications in astronauts, (b) monitoring in-flight changes in risk profile that may occur in the setting of deep space exploration, and (c) identifying endothelial susceptibility to the detrimental effects of space radiation. I oversee data collection and processing, coordinate with other statisticians and bioinformaticians on managing the data and performing statistical analyses.
U01 CA185094, NIH/NCI, Peters (PI), Site PI
Colorectal Tumor Risk Prediction in the PLCO Trial
The study will use detailed risk-factor information for colorectal cancer (CRC), including genome-wide genetic data as well as lifestyle and environmental risk factors, to build and validate a comprehensive risk-prediction model using data from a large CRC consortium and the PLCO trial as an independent validation study. As Co-I, I participate in the development of the models and the statistical advisory of the study.
T32 AI007358-23, Pagano (PI)
09/01/89-05/31/14
Biostatistics/Epidemiology Training Grants in AIDS
T32 AI007358-22, Pagano (PI)
09/01/89-05/31/14
Biostatistics/Epidemiology Training Grants in AIDS